[Hannah]: On the State of Medicine, 1860

"Throw out opium ... throw out a few specifics which our [physicians'] art did not discover, and is hardly needed to apply; throw out wine, which is a food, and the vapors which produced the miracle of anaesthesia, and I firmly believe that if the whole materia medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind - and all the worse for the fishes."

-Oliver Wendell Holmes, quoted in James Harvey Young, Pure Food